Royal Air Force Typhoon jets have joined forces with French warplanes in a coordinated attack targeting an hidden munitions depot in Syrian territory employed by the IS group, as stated by the UK's MoD.
The site, identified by intelligence, was thought to be containing munitions and bombs, the announcement noted, and was situated in mountainous terrain just north of Palmyra in the heart of Syria.
"Our fighter planes utilized precision-guided Paveway IV munitions to strike a number of approach shafts providing entry to the facility... early reports indicate the target was engaged successfully," the ministry announced.
There was no sign of any civilian impact in the strike conducted Saturday night and all the aircraft made a safe return, the MoD added.
The British jets were assisted by a Voyager tanker plane.
IS - referred to as the so-called Islamic State - imposed militant control over parts of both Syria and Iraq before its territorial defeat in 2019.
"This action shows British leadership, and commitment to stand shoulder to shoulder with our partners, to eliminate any revival of the terrorist group and their dangerous and violent ideologies in the area," Britain's Defence Chief the Defence Secretary said.
UK warplanes have conducted overwatch operations over Syria to "forestall any efforts to regroup" of the group after its routing at the Baghuz confrontation in 2019, the authorities noted.
"I extend gratitude to every member of the UK armed forces involved in this operation for their professionalism and their valour," he said. "They were part of numerous British personnel on duty over the festive period. This operation, to eliminate terrorist threats who pose a risk to our safety, demonstrates how British military are always on standby, continuously, protecting the UK at home and strong abroad."
Last December, the United States armed forces carried out what it termed a "major assault" against IS targets in the country, subsequent to an attack resulted in the deaths of two American soldiers and a local interpreter in Palmyra.
The United Nations estimates IS still maintains between 5,000 and 7,000 fighters in both countries.